Zhifang Chai

Professor Zhifang Chai, Academician, Doctoral Supervisor

Tel: 0512-65880035

Fax: 0512-65880035

E-mail: zfchai@sapatucson.com

Address: Room B302,Building 402, Soochow University, 199 Ren'ai Road, Suzhou 215123 (China)


Research Experience:

Prof. Zhifang Chai is a member of the Chinese Academy of Sciences. Now he serves as Dean of the School of Radiation Medicine and Protection and the School for Radiological and Interdisciplinary Science. He received his Bachelor's degree from Fudan University in 1964, majoring in radiation chemistry. From 1980-1982, he was funded by the Humboldt Scholarship and studied nuclear technology and application research at the University of Cologne in Germany. Since then, he has worked at Purdue University in the United States, the University of Strasbourg in France, the Delft University in the Netherlands, the ECN energy research center, and the University of Tokyo in Japan for a short period. He has devoted himself to the development of nuclear technology and nuclear analysis methodology and applied them to some interdisciplinary subjects for a long time. Thus, he has made impactful achievements in many fields, including molecule-neutron activation analysis of several important elements, thoroughly characterizing the family of platinum group elements, metallomics, environmental toxicology and nano security, and collecting the fast neutron spectrum in a nuclear explosion field. Professor Chai is now engaged in the research of radioactive medicine, nuclear energy chemistry and the nano-biological effect, and has been responsible for various major research programs, as well as major and key projects of the National Natural Science Foundation. He has published more than 500 papers in high-impact journals, most notably Nature and its series, Chem. Soc. Rev, PNAS, JACs, Nano Lett, etc., eight Chinese books, five English books, and given more than 50 seminars or keynote reports at international conferences. He has served or currently serves as a titular member of the International Union of Pure and Applied Chemistry (IUPAC), Fellow of the Royal Society of Chemistry, and as a member or consultant of five international academic organization committees, an editorial board member of four international and ten Chinese publications, including Radiochimica Acta, Metallomics and Science China, etc. Professor Chai has won nine National and Ministerial Awards, including the National Science Award, the second prize of National Natural Science Award, the second prize of National Science and Technology Progress Award, the first prize of Chinese Academy of Sciences Natural Science Award, etc. In 2005, he won the George Von Hevesy Award, which is the highest award in the field of international radio-analytical chemistry and nuclear chemistry, and was the first award winner coming from a developing country. In 2014, he was the Thomson Reuters Highly Cited Researcher in the Field of Pharmacology and Toxicology. Now, he is responsible for a major research project of the National Natural Science Foundation, 'Fuel Proliferation and Transmutation of Advanced Nuclear Fission'. Last, but not least, he is responsible for the Radiation Medicine Collaborative Innovation Center and Advantage Discipline of Special Medicine in Jiangsu province.


Main Research Field:

1.  Biological effects of high LET radiation

2.  Nuclear imaging methodology

3.  Environment radiochemistry

4.  Biological effects of nanomaterials

5.  The application of nano drugs in radiology


Research Projects:

1.  Project source: major program of National Natural Science Foundation; Project title: Fuel Proliferation and Transmutation of Advanced Nuclear Fission; Project number: 91026000; Project period: 2011.01-2017.12; Fund: 190 million yuan; Under research; Project leader.

2.  Project source: education department of Jiangsu province; Project title: Collaborative Innovation Center of Radiation Medicine; Project number: SX12800114; Project period: 2014.01-2017.12; Fund: 40 million yuan; Under research; Project leader.

3.  Project source: government of Jiangsu province; Project title: Advantage Discipline of Special Medicine; Project number: YX12800211; Project period: 2014.01-2017.12; Fund: 20 million yuan; Under research; Project leader.


Representative Papers:

Zhi-Qiang Bai, Li-Yong Yuan, Lin Zhu, Zhi-Rong Liu*, Sheng-Qi Chu, Li-Rong Zheng, Jing Zhang, Zhi-Fang Chai, Wei-Qun Shi*. Introduction of Amino Groups into Acid-resistant MOFs for Enhanced U(VI) Sorption. J. Mater. Chem. A. 2015; 3, 525-534. (IF=7.443)

Shi WQ, Yuan LY, Wang CZ, Wang L, Mei L, Xiao CL, Zhang L, Li ZJ,Zhao YL, ChaiZF. Exploring Actinide Materials Through Synchrotron Radiation Techniques. Adv. Mater. 2014; 26(46), 7807-7848. (IF=15.409)

Lei Mei, Qunyan Wu, Caiming Liu, Yu-liang Zhao, Zhifang Chai* and Wei-qun Shi*, The first case of actinide polyrotaxane incorporating cucurbituril: A unique 'dragon-like' twist inducedby a specific coordination pattern of uranium. Chem. Commun. 2014; 50, 3612-3615.  (IF=6.718)

Chunying Chen, Yu-Feng Li, Ying Qu, Zhifang Chai, Yuliang Zhao. Advanced nuclear analytical and related techniques for the growing challenges in nanotoxicology, Chem. Soc. Rev. 2013; 42, 8266-8303. (IF=24.892)

Zhanjun Gu, Liang Yan, Gan Tian, Shoujian Li, Zhifang Chai, Yuliang Zhao, Recent advances in design and fabrication of upconversion nanoparticles and their safe theranostic applications, Adv. Mater. 2013; 25, 3758-3779. (IF=14.829)

Weiting Yang, ZhiQiang Bai, WeiQun Shi*, LiYong Yuan, Tao Tian, ZhiFang Chai*, Hao Wang, Zhong-Ming Sun*. MOF-76: From Luminescent Probe to Highly Efficient UVI Sorption Material. Chem.Commun. 2013; 49: 10415-10417. (IF=6.378)

Ge CC, Du JF, Zhao LN, Wang LM, Liu Y, Li DH, Yang YL, Zhou RH, Zhao YL, Chai ZF, Chen CY. Binding of blood proteins to carbon nanotubes reduces cytotoxicity. Proc Natl Acad Sci USA. 2011 Oct; 108 (41): 16968-73. (IF=10.23)

He X, Zhang ZY, Liu JS, Ma YH, Zhang P, Li YY, Wu ZQ, Zhao YL, Chai ZF. Quantifying the biodistribution of nanoparticles. Nat. Nanotechnol. 2011; 6(12), 755 (IF=30.306)

Zhao YL, Xing GM, Chai ZF. Nanotoxicology: Are Carbon Nanotubes Safe? Nat. Nanotechnol. 2008; 3: 191-192. (IF=30.306)

10. Xu DY, Ma SL, Chai ZF, Mao XY, Sun YY, Zhang QW, Yang ZZ. Abundance variation of iridium and trace elements at the Permian / Triassic boundary at Shangsi in China. Nature. 1985; 314, 154-156. (IF=34.830)


Honors and Awards

1.   In 1978, the fast neutron excitation curve measurements of some nuclear, National Science Award, ranking fourth;

2.   In 1978, a study of the protection of water system of Guanting reservoir; National Science Award, ranking third;

3.   In 1983, a comprehensive study on the environment of Beijing, Tianjin, and Bohai Sea; the second price of National Science and Technology Progress Award, ranking sixth;

4.   In 1988, the application of nuclear analysis technology in environmental monitoring; the second prize of Chinese Academy of Sciences Science and Technology Progress Award, ranking first;

5.   In 1991, a study of the abundance characteristics of platinum group elements; the first prize of Chinese Academy of Sciences Natural Science Award, ranking first;

6.   In 1992, a study of molecular activation of iridium chemical species; American Nuclear Society Individual Award, ranking first;

7.   In 1999, a study of molecular activation of several important elements; the second prize of Chinese Academy of Sciences Natural Science Award, ranking fifth;

8.   In 2012, a study of the biological safety of nano-materials; the second price of National Natural Science Award, ranking fifth;

9.   In 2014, Thomson Reuters Highly Cited Researchers in the Field of Pharmacology and Toxicology;

10. In 2015, Medical Department of Soochow University Director Award, ranking first.


Course Information:

1.   Radiation Medicine Advances (undergraduate courses for seven-year program of clinical medicine in radiation medicine field)

2.   Nuclear Science Introduction (undergraduate courses)

3.   Lectures on the Frontiers of Medicine and Life Sciences (PhD courses)